TECHNOLOGY
Taming the Untamable
Taming the Untamable
Taming
the Untamable
Tagra’s advanced microencapsulation technologies solve
formulators toughest bench challenges, delivering exceptional
product performance from lab to scale.
Tagra’s cutting-edge encapsulation technology, delivering exceptional product performance and innovative solutions to your complex formulation challenges
THE BENCH REALITY
Every formula is
a negotiation between chemistry and the brief
High-performance cosmetics ask formulators to
hold instability, cross-reactivity and process friction in balance -
while raw material costs come down and launch dates move up.
A biodegradable cellulose-based polymer shell physically isolates a volatile or poorly soluble ingredient, turning an unstable liquid
into a stable, inert powder.
Actives degrade before delivery
Vitamin C, retinol and peptides degrade on contact with air, light, water or the wrong pH - and take the stability report down with them.
Vitamin C, retinol and peptides degrade on contact with air, light, water or the wrong pH - and take the stability report down with them.
Actives that cannot coexist
Multi-active briefs put ingredients in one emulsion that neutralise each other, forcing separation, sequestering or a smaller claim.
Multi-active briefs put ingredients in one emulsion that neutralise each other, forcing separation, sequestering or a smaller claim.
Actives that fight the process
Hydrophobic actives need heat, solvents and solubilisers to go into solution - and each one costs sensory, cost or stability elsewhere.
Hydrophobic actives need heat, solvents and solubilisers to go into solution - and each one costs sensory, cost or stability elsewhere.
What Tagra's microencapsulation does
What Tagra's
microencapsulation does
A biodegradable cellulose-based polymer shell physically isolates
a volatile or poorly soluble ingredient, turning an unstable liquid
into a stable, inert powder.
A biodegradable cellulose-based polymer shell physically isolates a volatile or poorly soluble ingredient, turning an unstable liquid
into a stable, inert powder.
Prevents oxidation
No degradation or browning
in the jar across shelf life.
No degradation or browning
in the jar across shelf life.
Ends cross-reactivity
Incompatible actives sit in the same base without touching.
Release on demand
RND™ holds through manufacture and ruptures under friction on skin.
RND™ holds through manufacture and ruptures under friction on skin.
Format freedom
A dry powder disperses into creams, gels, sticks and anhydrous systems.
A dry powder disperses into creams, gels, sticks and anhydrous systems.
MICROENCAPSULATION PLATFORM
Three technologies
for distinct formulation challenges
Address different formulation challenges – from protecting and
releasing actives to isolating UV filters and making poorly soluble
ingredients water-soluble.
Three distinct technologies address different formulation challenges–from protecting and releasing actives to isolating UV filters and making poorly soluble ingredients
water-soluble.
Microcapsules
Technology
Microcapsules
Technology
Breakable
Microcapsules
Breakable
Microcapsules
Breakable
Microcapsules
Tagra has developed a Microencapsulation Technology based on
a Release on Demand (RND™) patented method, for non-water-soluble ingredients. Those breakable microcapsules enable optimal isolation, preventing diffusion of the encapsulated material into the formulation. They provide stable, efficient, controlled, and immediate release. The encapsulation itself makes it possible to overcome incompatibilities between different ingredients comprising the formulation.
The encapsulant is optimally protected from all environmental risk factors: light, temperature, pH, oxidation, and interaction with other ingredients. Although impermeable, the polymer shell is elastic in nature, and is easily ruptured upon application of mechanical pressure such as a rubbing action.
The encapsulant is optimally protected from all environmental risk factors: light, temperature, pH, oxidation, and interaction with other ingredients. Although impermeable, the polymer shell is elastic in nature, and is easily ruptured upon application of mechanical pressure such as a rubbing action.
Unbreakable
Microcapsules
Unbreakable
Microcapsules
Unbreakable
Microcapsules
SunCaps™ microcapsules are made of a single layer Cellulose based polymer shell which provides optimal isolation of the UV filter and prevents its degradation while improving its UV protection profile.
SunCaps™ microcapsules are made of a single layer Cellulose based polymer shell which provides optimal isolation of the UV filter and prevents its degradation while improving its UV protection profile.
Tagra’s unique patented technology enables the manufacturing of
plant-derived cellulose, unbreakable, transparent micron size microcapsules of organic and inorganic UV filters.
Water-Soluble
Microcapsules
Water-Soluble
Microcapsules
Water-Soluble
Microcapsules
Many active compounds, skin, scalp, and hair treatment materials are substantially insoluble in water. There are several different approaches to solve the solubility problem of poorly water-soluble compounds. Tagra’s technology applies an innovative and sophisticated approach to overcome this issue by converting non-water-soluble compounds to very soluble ones.
Many active compounds, skin, scalp, and hair treatment materials are substantially insoluble in water. There are several different approaches to solve the solubility problem of poorly water-soluble compounds. Tagra’s technology applies an innovative and sophisticated approach to overcome this issue by converting non-water-soluble compounds to very soluble ones.
The technology outcome is a water-soluble powder containing a non-water-soluble compound. This outcome was achieved by applying a technique of complexation of a water insoluble compound with polymers and medium chain fatty acids and other additives.
The technology outcome is a water-soluble powder containing a non-water-soluble compound. This outcome was achieved by applying a technique of complexation of a water insoluble compound with polymers and medium chain fatty acids and other additives.
The final step of preparing the water-soluble powder formulation, comprising high weight percentages of a water-insoluble organic compound is a spray drying process, leads to immediate conversion of the complex of materials, into microcapsules. These particles exhibit properties in view of their solubility properties, and degree of non-crystallinity.
The final step of preparing the water-soluble powder formulation, comprising high weight percentages of a water-insoluble organic compound is a spray drying process, leads to immediate conversion of the complex of materials, into microcapsules. These particles exhibit properties in view of their solubility properties, and degree of non-crystallinity.
FROM BENCH TO VAT
The capsule
survives the scale-up
A formula that works in a 100 g beaker usually has to be rebuilt for a production vat. This one does not – the capsule arrives as a finished raw material and goes in at the very last step.
A biodegradable cellulose-based polymer shell physically isolates a volatile or poorly soluble ingredient, turning an unstable liquid
into a stable, inert powder.
85
℃
Process temperature
the shell withstands intact
Process temperature
the shell withstands intact
Added at
the last step
A dry powder dropped into the cool-down phase. No change to the existing process.
A dry powder dropped into the cool-down phase. No change to the existing process.
Simple
paddle mixing
No homogeniser, no high shear, no specialised equipment to disperse it evenly.
Consistent at
any batch size
The same behaviour from bench trial to full production run – no reformulation on the way up.
The same behaviour from bench trial to full production run – no reformulation on the way up.
Protected until
the moment of use
No leakage or premature breakage during production, packaging
or storage.
No leakage or premature breakage during production, packaging
or storage.
Benefits
Benefits
Benefits
Upsides of Encapsulated Materials for Formulators and Consumers
Upsides of Encapsulated Materials for Formulators and Consumers
Upsides of Encapsulated Materials for Formulators and Consumers
Tagra’s breakable microcapsules create visual and sensorial effects, including color and texture transitions, that engage and delight the end consumer. Stabilized actives are delivered fresh with Release on Demand (RND™) technology to help provide improved skincare benefits.
Tagra’s breakable microcapsules create visual and sensorial effects, including color and texture transitions, that engage and delight the end consumer. Stabilized actives are delivered fresh with Release on Demand (RND™) technology to help provide improved skincare benefits.
Tagra’s breakable microcapsules create visual and sensorial effects, including color and texture transitions, that engage and delight the end consumer. Stabilized actives are delivered fresh with Release on Demand (RND™) technology to help provide improved skincare benefits.
Enhanced Stability and Improve Compatibility
Enhanced Stability and Improve Compatibility
Seamless Scale-Up
Seamless Scale-Up
Flexibility
Flexibility
Expert R&D Support
Expert R&D Support
Environment Friendly
Environment Friendly
The Production Process
The Production Process
The Production Process
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